Fishwick D, Bradshaw L M, Slater T, Pearce N
Wellington Asthma Research Group, Department of Medicine, Wellington School of Medicine, New Zealand.
Scand J Work Environ Health. 1997 Oct;23(5):351-8. doi: 10.5271/sjweh.231.
The possibility was investigated that exposure to welding fumes causes an acute decrease in pulmonary function.
Changes in the pulmonary function of 62 current welders and 75 nonwelders at the same sites and the relationship with work-related symptoms were recorded.
Work-related cough was reported by 22.6% of the current welders and 6.7% of the nonwelders [odds ratio (OR) 4.1, 95% confidence interval (95% CI) 1.5-11.5], and the respective figures for at least 1 work-related symptom were 30.7% and 16.0% (OR 2.3, 95% CI 1.0-5.2). The groups' preshift lung function did not differ. The mean percentage change from the base-line value of the forced expiratory volume in 1 s (FEV1.0) after 15 minutes of work was -2.8% (range -29.3% to +20.9%) for the current welders and +1.0% (range -20.7% to +22.6%) for the nonwelders (P = 0.01). A multivariate analysis identified current welding as the most significant risk factor for a decrease of at least 5% in FEV1.0 after 15 minutes, the risk being greater for those with no local exhaust ventilation (OR 22.4, 95% CI 4.5-113.4) than for those with personal protection only (OR 16.0, 95% CI 2.1-122.9) and those with local exhaust ventilation (OR 2.8, 95% CI 0.2-41.2) or passive exposure only (OR 2.0, 95% CI 0.5-8.8).
An acute decrease in FEV1.0 in relation to work is more prevalent among welders than among nonwelders, and is more common among welders without local exhaust ventilation than among those with it.
研究接触焊接烟雾是否会导致肺功能急性下降。
记录了62名在职焊工和75名同一工作地点非焊工的肺功能变化情况以及与工作相关症状的关系。
22.6%的在职焊工和6.7%的非焊工报告有与工作相关的咳嗽[比值比(OR)4.1,95%置信区间(95%CI)1.5 - 11.5],至少有1种与工作相关症状的比例分别为30.7%和16.0%(OR 2.3,95%CI 1.0 - 5.2)。两组班前肺功能无差异。工作15分钟后,在职焊工1秒用力呼气量(FEV1.0)相对于基线值的平均百分比变化为-2.8%(范围为-29.3%至+20.9%),非焊工为+1.0%(范围为-20.7%至+22.6%)(P = 0.01)。多因素分析确定当前焊接是工作15分钟后FEV1.0至少下降5%的最显著危险因素,对于没有局部排气通风的人(OR 22.4,95%CI 4.5 - 113.4),风险高于仅使用个人防护的人(OR 16.0,95%CI 2.1 - 122.9)以及有局部排气通风的人(OR 2.8,95%CI 0.2 - 41.2)或仅被动接触的人(OR 2.0,95%CI 0.5 - 8.8)。
与工作相关的FEV1.0急性下降在焊工中比在非焊工中更普遍,并且在没有局部排气通风的焊工中比有局部排气通风的焊工中更常见。