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[一名有脑血管并发症家族史的高血压患者的肾纤维肌性发育异常与脑动脉瘤]

[Renal fibromuscular dysplasia and cerebral aneurysm in a hypertensive patient with a familial history of cerebral vascular complications].

作者信息

Persu A, Dubois C, Pirson Y, de Plaen J F

机构信息

Service de Néphrologie, Cliniques Universitaires Saint Luc, Université Catholique de Louvain, Bruxelles, Belgique.

出版信息

Presse Med. 1997 Oct 11;26(30):1429-31.

PMID:9404355
Abstract

BACKGROUND

The possibility of an association between two vascular anomalies, renal artery dysplasia and cerebral artery aneurysm, merits recognition.

CASE REPORT

We report the case of a 63 year old woman who was found to have fibromuscular dysplasia affecting the right renal artery while being investigated for systemic hypertension. Given a family history of cerebrovascular accident occurring before the age of 50, a cerebral angiogram was performed which demonstrated a saccular aneurysm of the middle cerebral artery measuring 6 mm in diameter.

DISCUSSION

The association of these two anomalies could result from a familial arterial fibromuscular dysplasia. There are practical implications, notably the risk of aneurysm rupture and the role of hypertension.

摘要

背景

两种血管异常情况,即肾动脉发育异常和脑动脉瘤之间存在关联的可能性值得关注。

病例报告

我们报告了一名63岁女性的病例,该患者在因系统性高血压接受检查时,被发现患有影响右肾动脉的纤维肌性发育不良。鉴于其家族中有50岁之前发生脑血管意外的病史,遂进行了脑血管造影,结果显示大脑中动脉有一个直径为6毫米的囊状动脉瘤。

讨论

这两种异常情况的关联可能源于家族性动脉纤维肌性发育不良。这具有实际意义,尤其是动脉瘤破裂的风险以及高血压的作用。

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