青少年慢性粒单核细胞白血病：分子与新型治疗基础
Juvenile chronic myelomonocytic leukemias: molecular and novel therapeutic basis.
作者信息
Chomienne C, Cambier N, Baruchel A
机构信息
Laboratoire de Biologie Cellulaire Hématopoïétique EP CNRS 107, Hôpital Saint-Louis, Paris, France.
出版信息
Pathol Biol (Paris). 1997 Sep;45(7):600-4.
PMID:9404486
Abstract
Myelomonocytic leukemias of children represent a distinct disorder from chronic myelogenous leukemia and adult myelomonocytic leukemias. The prognosis is poor and no therapy has proved to be yet effective. This review summarizes the molecular and cellular characteristics of this disease which may allow to design more targetted therapeutic agents.
摘要
儿童骨髓单核细胞白血病是一种有别于慢性粒细胞白血病和成人骨髓单核细胞白血病的独特疾病。其预后较差，尚无治疗方法被证明有效。本综述总结了该疾病的分子和细胞特征，这可能有助于设计更具针对性的治疗药物。
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