Baudard M, Delmer A, Zittoun R
Service d'Hématologie Clinique, Hôpital Hôtel-Dieu, Paris, France.
Pathol Biol (Paris). 1997 Sep;45(7):605-11.
Chronic myelomonocytic leukemia (CMML) is characterized by the association of myelodysplastic features and proliferation of both granulocytic and monocytic series. This disease frequently indolent, may however demonstrate progressive course and/or transform to acute leukemia. Nosologic and diagnostic problems raised by this malignant hematological pathology, its clinical and biological presentations, and current treatments are reported in this review.
慢性粒单核细胞白血病(CMML)的特征是骨髓发育异常特征以及粒细胞系和单核细胞系的增殖。这种疾病通常进展缓慢,但可能会呈现进行性病程和/或转化为急性白血病。本文综述了这种恶性血液病理学引发的分类学和诊断问题、其临床和生物学表现以及当前的治疗方法。