Lin R Y, Du S L, Yeh H S, Wang W M
Department of Dermatology, Tri-Service General Hospital, Taipei, Taiwan, Republic of China.
Dermatology. 1997;195(3):271-3. doi: 10.1159/000245959.
Case reports about vasopressin-induced cutaneous necrosis are not frequent. Here we report a further case, of which skin manifestations included not only mottling, cyanosis, ecchymosis, bullae and gangrene, but also amber-like change in focal areas. Besides, intermittent paling of the skin with or without deep pain sensation of the limbs over non-injection sites was observed that might be a warning sign of impending skin necrosis. Based on the literature about vasopressin-induced skin necrosis we discuss the possible role of coagulation enhancement of this molecule.
关于血管加压素引起皮肤坏死的病例报告并不常见。在此，我们报告另一例病例，其皮肤表现不仅包括斑纹、发绀、瘀斑、水疱和坏疽，还包括局部区域的琥珀样改变。此外，在非注射部位观察到皮肤间歇性变白，伴有或不伴有四肢深部疼痛感觉，这可能是即将发生皮肤坏死的警示信号。基于有关血管加压素引起皮肤坏死的文献，我们讨论了该分子凝血增强的可能作用。
