Lin M C, Liaw M Y, Huang C C, Tsai Y H
Department of Medicine, Chang Gung Memorial Hospital, Taipei, Taiwan, ROC.
J Formos Med Assoc. 1997 Nov;96(11):869-73.
A multidisciplinary pulmonary rehabilitation program was conducted for 13 outpatients (mean age 66 +/- 6.7 yr) with moderately severe chronic obstructive pulmonary disease. Changes in pulmonary function and blood gas data were not significant. Exercise capability, including 6-minute walking distance (WkD6), maximal work load (WkLmax), endurance time, and maximum heart rate, improved significantly (p < 0.05), as did subjective symptoms and quality of life. Of the observed changes, only baseline PaO2 and oxygen saturation were positively correlated with changes in maximum heart rate. The initial maximum heart rate was inversely related to both the absolute and percentage improvement. There were no significant relationships between improvement in WkD6 and age, initial arterial blood gas, or pulmonary function, but a significant relationship was found between baseline forced expired volume in the first second (FEV1) and percentage change in WkLmax. Our results indicate that patients with moderately severe chronic obstructive pulmonary disease can improve their exercise capacity, subjective symptoms, and quality of life through a pulmonary rehabilitation program. All patients can increase their endurance, regardless of their initial exercise performance. Maximum heart rate and FEV1 are predictors of exercise capability improvement.
对13例中度严重慢性阻塞性肺疾病门诊患者（平均年龄66±6.7岁）实施了多学科肺康复计划。肺功能和血气数据的变化不显著。运动能力，包括6分钟步行距离（WkD6）、最大工作量（WkLmax）、耐力时间和最大心率，均有显著改善（p<0.05），主观症状和生活质量也有所改善。在观察到的变化中，只有基线PaO2和血氧饱和度与最大心率的变化呈正相关。初始最大心率与绝对改善率和百分比改善率均呈负相关。WkD6的改善与年龄、初始动脉血气或肺功能之间无显著关系，但在基线第一秒用力呼气量（FEV1）与WkLmax的百分比变化之间发现了显著关系。我们的结果表明，中度严重慢性阻塞性肺疾病患者可通过肺康复计划改善运动能力、主观症状和生活质量。所有患者均可提高耐力，无论其初始运动表现如何。最大心率和FEV1是运动能力改善的预测指标。
