Yamanouchi H, Mizutani T, Matsushita S, Esaki Y
Department of Neurology, Tokyo Metropolitan Geriatric Hospital, Japan.
Neurology. 1997 Dec;49(6):1691-4. doi: 10.1212/wnl.49.6.1691.
We examined brains clinicopathologically from 54 consecutive paroxysmal atrial fibrillation (PAF) patients aged 70 years or older and compared them with those of 59 age-matched controls. Symptomatic cerebral infarctions were present in 29 PAF patients (53.7%) and in 13 controls (22.0%) (p < 0.001). Symptomatic brain infarction was 2.4 times more common in PAF cases than in PAF-free controls; approximately 60% of the infarctions in the PAF cases were judged to be cardioembolic in origin. PAF in the elderly can be an important cause for cardiogenic cerebral embolism.
我们对54例年龄在70岁及以上的连续性阵发性心房颤动（PAF）患者的大脑进行了临床病理检查，并将其与59例年龄匹配的对照者的大脑进行了比较。29例PAF患者（53.7%）和13例对照者（22.0%）出现了症状性脑梗死（p<0.001）。有症状的脑梗死在PAF病例中比无PAF的对照者中常见2.4倍；PAF病例中约60%的梗死被判定为心源性栓塞所致。老年人的PAF可能是心源性脑栓塞的一个重要原因。
