Wen P Y, Alyea E P, Simon D, Herbst R S, Soiffer R J, Antin J H
Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA.
Neurology. 1997 Dec;49(6):1711-4. doi: 10.1212/wnl.49.6.1711.
We describe four patients who developed Guillain-Barré syndrome (GBS) following allogeneic bone marrow transplantation (BMT). All four patients had a febrile illness before developing GBS. Two patients had mild graft-versus-host disease but did not require immunosuppression. These patients add to the increasing number of BMT patients whose courses have been complicated by GBS and raise the possibility that BMT patients, especially those undergoing allogeneic BMT, may have a higher risk of developing GBS.
我们描述了4例在异基因骨髓移植(BMT)后发生吉兰-巴雷综合征(GBS)的患者。所有4例患者在发生GBS之前均有发热性疾病。2例患者有轻度移植物抗宿主病,但不需要免疫抑制治疗。这些患者增加了BMT后病程并发GBS的患者数量,并提示BMT患者,尤其是接受异基因BMT的患者,发生GBS的风险可能更高。