Influence of morphine on protein synthesis in discrete subcellular fractions of the rat brain.
作者信息
Hitzemann R J, Loh H H
出版信息
Res Commun Chem Pathol Pharmacol. 1976 Jun;14(2):237-48.
PMID:940957
Abstract
Extensive time course (15 min to 24 hr) measurements were made of the effects of acute and chronic morphine treatment on the incorporation of 3H-lysine into rat brain proteins. Acute and chronic morphine treatment inhibited cortical protein synthesis in the microsomal (Mc), mitochondrial (Mw) and soluble fractions (Sol.). In the subcortex, acute morphine stimulated labelled protein accumulation in the Mc and Mw fractions, Chronic morphine treatment decreased 3H-lys-protein accumulation in these fractions.
摘要
相似文献
1
Influence of morphine on protein synthesis in discrete subcellular fractions of the rat brain.
Res Commun Chem Pathol Pharmacol. 1976 Jun;14(2):237-48.
2
Influence of morphine on protein synthesis in synaptic plasma membranes of the rat brain.
Res Commun Chem Pathol Pharmacol. 1977 May;17(1):15-28.
3
Amino acid incorporation during morphine intoxication. I: Dose and time effects of morphine on protein synthesis in specific regions of the rat brain and in astroglia-enriched primary cultures.吗啡中毒期间的氨基酸掺入。I：吗啡对大鼠脑特定区域及富含星形胶质细胞的原代培养物中蛋白质合成的剂量和时间效应。
J Neurosci Res. 1985;14(4):461-77. doi: 10.1002/jnr.490140408.
4
Influence of morphine, beta-endorphin and naloxone on the synthesis of phosphoinositides in the rat midbrain.
Res Commun Chem Pathol Pharmacol. 1979 May;24(2):233-50.
5
Effects of acute and chronic morphine administration on the incorporation of (3H)-lysine into mouse brain and liver proteins.
Res Commun Chem Pathol Pharmacol. 1974 Oct;9(2):299-306.
6
Protein and ribonucleic acid metabolism in brain of mice following chronic alcohol consumption.长期饮酒后小鼠大脑中的蛋白质和核糖核酸代谢
Vopr Biokhim Mozga. 1973;8:317-30.
7
Mitochondria and protein synthesis in brain.
Adv Biochem Psychopharmacol. 1969;1:165-79.
8
Uptake into brain proteins of 35S-methionine during morphine tolerance.吗啡耐受期间35S-甲硫氨酸在脑蛋白中的摄取。
J Pharmacol Exp Ther. 1975 Mar;192(3):521-30.
9
The effect of morphine tolerance on the incorporation of 3H-leucine into proteins of rat synaptic membranes.
J Neurosci Res. 1979;4(2):93-103. doi: 10.1002/jnr.490040203.
10
Rates of amino acid incorporation into particulate proteins in vivo and in slices of young and adult brain.体内以及幼年和成年大脑切片中氨基酸掺入颗粒蛋白的速率。
J Neurosci Res. 1986;15(3):359-66. doi: 10.1002/jnr.490150307.
引用本文的文献
1
Are astroglial cells involved in morphine tolerance?星形胶质细胞与吗啡耐受性有关吗？
Neurochem Res. 1988 Feb;13(2):87-103. doi: 10.1007/BF00973320.
Zotero 插件