Gebel T, Dunkelberg H
Abteilung für Allgemeine Hygiene und Umweltmedizin, Zentrum Umwelt- und Arbeitsmedizin, Universität Göttingen.
Zentralbl Hyg Umweltmed. 1996 Nov;199(1):69-75.
It had been shown previously by various authors that contact of amalgam fillings to metal fillings of different type can increase the electrochemically caused amalgam corrosion in vitro thus leading to an elevated release of mercury. So it was recommended to renounce of a dental contact of amalgam to metal fillings of other type. One aim of the present study was to evaluate possible influences of this contact in vivo on the urinary mercury contents in human volunteers. Neither approximal nor occlusal contacts had any influence on the urinary mercury excretion in comparison to a reference group with similar amalgam status. Furthermore, the influence of gum chewing on urinary mercury levels was taken into account. It could be shown that the consumption of chewing gum resulted in a significantly higher mean urinary mercury content in probands with amalgam fillings in comparison to people with similar amalgam status (gum chewers: 1.36 Hg/24 h vs. non-chewers 0.70 microgram Hg/24 h). Thus, gum chewing has to be considered as important parameter of influence on the urinary mercury levels of people with amalgam fillings.
此前已有多位作者表明，汞合金填充物与不同类型的金属填充物接触，可在体外增加电化学引起的汞合金腐蚀，从而导致汞释放量升高。因此，建议避免汞合金与其他类型金属填充物的牙齿接触。本研究的一个目的是评估这种接触在体内对人类志愿者尿汞含量的可能影响。与具有相似汞合金状况的参考组相比，邻面接触和咬合接触对尿汞排泄均无影响。此外，还考虑了咀嚼口香糖对尿汞水平的影响。结果表明，与具有相似汞合金状况的人群相比，咀嚼口香糖的汞合金填充物受试者的平均尿汞含量显著更高（咀嚼口香糖者：1.36微克汞/24小时，非咀嚼者：0.70微克汞/24小时）。因此，咀嚼口香糖必须被视为影响汞合金填充物人群尿汞水平的重要参数。
