Marrón A, Formiga F, Valverde J, Mitjavila F, Pac M, Moga I
Servicio de Medicina Interna, Hospital Princeps d'Espanya, CSU de Bellvitge, Barcelona.
An Med Interna. 1997 Jun;14(6):307-9.
We present three cases of patients with systemic lupus erythematosus (SLE) and osteonecrosis or avascular necrosis (AV). Although, the pathogenesis of osteonecrosis is controversial and multifactorial, the glucocorticoids therapy is the most important factor contributing to the lesion. We report the clinical presentation of the three patients. We comment the characteristics of AV, the diagnosis and the treatment of this uncommon complication in SLE patients.
我们报告了三例系统性红斑狼疮(SLE)合并骨坏死或缺血性坏死(AV)的患者。尽管骨坏死的发病机制存在争议且是多因素的,但糖皮质激素治疗是导致该病变的最重要因素。我们报告了这三名患者的临床表现。我们对SLE患者中这种罕见并发症的AV特征、诊断和治疗进行了评论。