Liñana J J, Montoro F J, Hernández M D, Basomba A
Servicio de Alergia, Hospital Universitari La Fe, Valencia.
An Med Interna. 1997 Jul;14(7):369-72.
The prevalence of allergic reactions to insuline has decreased during the last few years. Probably this is due to the use of the newly-developed recombinant human insuline. At present, adverse reactions to insuline occur in 5-10% of patients on therapy with insuline. Adverse reactions may be local (more frequent) or systemic (rare). Insuline resistance consists in a different type of immunological reaction. Diagnosis of allergy to insuline is based on clinical history and cutaneous and serological tests. Treatment depends upon the severity of the reaction. When insuline is indispensable despite a previous allergic reaction, a desensitization protocol may be implemented.
在过去几年中，胰岛素过敏反应的发生率有所下降。这可能是由于使用了新开发的重组人胰岛素。目前，接受胰岛素治疗的患者中有5%-10%会出现胰岛素不良反应。不良反应可能是局部的（更常见）或全身性的（罕见）。胰岛素抵抗是一种不同类型的免疫反应。胰岛素过敏的诊断基于临床病史以及皮肤和血清学检查。治疗取决于反应的严重程度。尽管之前有过敏反应，但当胰岛素不可或缺时，可以实施脱敏方案。
