Weischer T, Mohr C
Klinik und Poliklinik für Gesichts- und Kieferchirurgie, Essen.
Mund Kiefer Gesichtschir. 1997 Sep;1(5):294-9. doi: 10.1007/BF03043570.
After resection of an oropharyngeal tumor, 157 dental implants were placed in 17 irradiated (44 Gy on average) and 20 non-irradiated patients. Within a control period of 37 months, 15 implants had failed. The reason for implant failure was analyzed, whereby indicative parameters were revealed. Eleven implants in four irradiated and one non-irradiated oral cancer patients showed no primary osseointegration during the healing period because of mandible fracture, overloading or for unknown reasons. Four implants in one irradiated and three non-irradiated oral-cancer patients were lost subsequently on average 39 months after second-stage surgery due to biomechanical overloading or bacterial infection. No osteoradionecrosis development due to implant failure was observed in irradiated patients. In all cases, peri-implant pocket depth, implant stability and peri-implant bone resorption increased before definitive implant failure. Therefore, these findings seem to be useful as indicative parameters in the prediction of implant failure.
在切除口咽肿瘤后,对17名接受过放疗(平均剂量44 Gy)的患者和20名未接受过放疗的患者植入了157颗牙种植体。在37个月的对照期内,有15颗种植体失败。分析了种植体失败的原因,从而揭示了指示性参数。4名接受过放疗的口腔癌患者和1名未接受过放疗的患者中,有11颗种植体在愈合期因下颌骨骨折、负荷过重或不明原因而未实现初期骨整合。1名接受过放疗的口腔癌患者和3名未接受过放疗的口腔癌患者中的4颗种植体在二期手术后平均39个月因生物力学负荷过重或细菌感染而随后丢失。在接受过放疗的患者中,未观察到因种植体失败而发生放射性骨坏死。在所有病例中,在种植体最终失败前,种植体周围袋深度、种植体稳定性和种植体周围骨吸收均增加。因此,这些发现似乎可作为预测种植体失败的指示性参数。