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A Myc-induced apoptosis pathway surfaces.

作者信息

Green D R

机构信息

Division of Cellular Immunology, La Jolla Institute for Allergy and Immunology, San Diego, CA 92121, USA.

出版信息

Science. 1997 Nov 14;278(5341):1246-7. doi: 10.1126/science.278.5341.1246.

DOI:10.1126/science.278.5341.1246
PMID:9411752
Abstract
摘要

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A Myc-induced apoptosis pathway surfaces.一条由Myc诱导的凋亡途径浮现出来。
Science. 1997 Nov 14;278(5341):1246-7. doi: 10.1126/science.278.5341.1246.
2
Requirement for the CD95 receptor-ligand pathway in c-Myc-induced apoptosis.c-Myc诱导的细胞凋亡中CD95受体-配体途径的需求
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Deregulated c-Myc prematurely recruits both Type I and II CD95/Fas apoptotic pathways associated with terminal myeloid differentiation.失调的c-Myc过早地募集与终末髓系分化相关的I型和II型CD95/Fas凋亡途径。
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c-Myc-induced sensitization to apoptosis is mediated through cytochrome c release.c-Myc诱导的细胞凋亡敏感性是通过细胞色素c的释放介导的。
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Ceramide-induced cell death is independent of the Fas/Fas ligand pathway and is prevented by Nur77 overexpression in A20 B cells.神经酰胺诱导的细胞死亡不依赖于Fas/Fas配体途径,并且在A20 B细胞中过表达Nur77可阻止这种细胞死亡。
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Cell death induction by TNF: a matter of self control.肿瘤坏死因子诱导的细胞死亡:自我控制的问题。
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Involvement of CPP32/Caspase-3 in c-Myc-induced apoptosis.CPP32/半胱天冬酶-3参与c-Myc诱导的细胞凋亡。
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Interleukin-8-induced suppression of polymorphonuclear leukocyte apoptosis is mediated by suppressing CD95 (Fas/Apo-1) Fas-1 interactions.白细胞介素-8诱导的多形核白细胞凋亡抑制是通过抑制CD95(Fas/Apo-1)Fas-1相互作用介导的。
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J Cereb Blood Flow Metab. 2001 Dec;21(12):1411-21. doi: 10.1097/00004647-200112000-00005.

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