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[细胞与身体衰老过程中遗传损伤和随机损伤之间的关系]

[The relationship between genetic and stochastic damage during the process of cell and bodily aging].

作者信息

Berdyshev G D

出版信息

Tsitol Genet. 1976 Jan-Feb;10(1):64-72.

PMID:941265
Abstract

The paper deals with the conception formulated by the author concerning the dual nature of the ageing process determined by genetic and random factors which manifest their action at the molecular, cellular and organism level. The review is given of the author's own studies in the ratio of programmed and stochastic mechanisms of ageing in different organisms and cells in the tissue culture. A conclusion is made that genetic factors are the leading ones in determining the main mechanisms of ageing.

摘要

本文论述了作者提出的关于衰老过程双重性质的概念,该过程由遗传和随机因素决定,这些因素在分子、细胞和机体水平上发挥作用。文中回顾了作者自己对不同生物体以及组织培养中的细胞衰老的程序性机制和随机机制比例的研究。得出的结论是,遗传因素在决定衰老的主要机制中起主导作用。

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