与腺瘤及腺癌相关的结直肠增生性（化生型）息肉病

Hyperplastic (metaplastic) polyposis of the colorectum associated with adenomas and an adenocarcinoma.

作者信息

Orii S, Nakamura S, Sugai T, Habano W, Akasaka I, Nakasima F, Kazama H, Hasimoto Y, Takahasi H, Sugawara M, Sato S

机构信息

First Department of Internal Medicine, School of Medicine, Iwate Medical University, Morioka, Japan.

出版信息

J Clin Gastroenterol. 1997 Jul;25(1):369-72. doi: 10.1097/00004836-199707000-00018.

DOI:10.1097/00004836-199707000-00018

PMID:9412925

Abstract

Hyperplastic (metaplastic) polyposis associated with adenoma and adenocarcinoma of the colorectum is rare. We describe a 55-year-old man with hyperplastic polyposis associated with multiple adenomas and an adenocarcinoma who underwent total colectomy. We found at least 200 polyps in the surgical specimen. Nearly all of the polyps were hyperplastic, and some were adenomas. Furthermore, some hyperplastic polyps had adenomatous areas. This indicates the transformational sequence of a hyperplastic polyp to adenoma to adenocarcinoma.

摘要

与结直肠癌腺瘤和腺癌相关的增生性（化生型）息肉病很罕见。我们描述了一名55岁患有增生性息肉病并伴有多个腺瘤和1例腺癌的男性患者，该患者接受了全结肠切除术。我们在手术标本中发现了至少200个息肉。几乎所有息肉都是增生性的，有些是腺瘤。此外，一些增生性息肉有腺瘤样区域。这表明了增生性息肉向腺瘤再向腺癌的转变过程。