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首次发作的腰痛的一年随访。

One-year follow-up of first onset low back pain.

作者信息

Wahlgren Dennis R, Atkinson Hampton J, Epping-Jordan JoAnne E, Williams Rebecca A, Pruitt Sheri D, Klapow Joshua C, Patterson Thomas L, Grant Igor, Webster John S, Slater Mark A

机构信息

Research, Psychiatry, and Psychology Services, VA San Diego Healthcare System, 3350 La Jolla Village Drive, San Diego, CA 92161 USA Center for Behavioral Epidemiology and Community Health, Graduate School of Public Health, San Diego State University, San Diego, CA, USA Department of Psychiatry, School of Medicine, University of California at San Diego, San Diego, CA, USA Department of Orthopaedics, Naval Medical Center, San Diego, CA, USA Research and Development, Sharp Health Care, San Diego, CA, USA.

出版信息

Pain. 1997 Nov;73(2):213-221. doi: 10.1016/S0304-3959(97)00106-1.

Abstract

Efforts to examine the process and risk of developing chronic back pain have relied generally upon retrospective study of individuals with already established pain. In an alternative approach to understanding the clinical course and evolution of low back disorders, a cohort of 76 men experiencing their first episode of back pain was assessed prospectively at 2, 6 and 12 months following pain onset. Standard measures of pain (Descriptor Differential Scale: DDS), disability (Sickness Impact Profile: SIP), and distress (Beck Depression Inventory: BDI) were employed to classify the sample into five groups: Resolved, Pain Only, Disability/Distress Only, Pain and Mild Disability/Distress, and Clinical Range. At both 6 and 12 months post pain onset, most (78%, 72% respectively) of the sample continued to experience pain. Many also experienced marked disability at 6 months (26%) and 12 months (14%). At 12 months, no participants had worsened relative to the 2-month baseline. Doubly multivariate analyses of variance (MANOVAs) were employed to compare baseline groups (Pain Only, Pain and Mild Disability/Distress, Clinical Range) on the DDS, SIP, and BDI across time. The group by time interaction from 2 through 12 months was reliable, with greatest change occurring in the Clinical Range group in disability and distress; interestingly, the decrease in pain was comparable among all groups. Follow-up tests across measures demonstrated greater change in the early (2-6-month) interval and relative stability in the later (6-12-month) interval. Comparison of those classified as 'improvers' with those who did not improve from 2 to 12 months showed similar findings. The clinical course of first onset back pain may be prolonged for many patients, and involves a continuum of related disability and distress. Individuals at risk for marked symptoms 1 year after an initial episode of back pain can be identified early, and prompt treatment might reduce the risk of pain chronicity.

摘要

研究慢性背痛发生过程和风险的努力通常依赖于对已有疼痛个体的回顾性研究。作为理解下背部疾病临床过程和演变的另一种方法,对76名首次经历背痛发作的男性队列在疼痛发作后的2个月、6个月和12个月进行了前瞻性评估。采用疼痛的标准测量方法(描述符差异量表:DDS)、残疾(疾病影响概况:SIP)和痛苦(贝克抑郁量表:BDI)将样本分为五组:已缓解、仅疼痛、仅残疾/痛苦、疼痛伴轻度残疾/痛苦和临床范围组。在疼痛发作后的6个月和12个月时,大多数样本(分别为78%、72%)仍持续疼痛。许多人在6个月(26%)和12个月(14%)时也出现了明显的残疾。在12个月时,没有参与者相对于2个月的基线情况恶化。采用双因素多变量方差分析(MANOVA)来比较基线组(仅疼痛、疼痛伴轻度残疾/痛苦、临床范围组)在不同时间点的DDS、SIP和BDI。从2个月到12个月的组间时间交互作用是可靠的,临床范围组在残疾和痛苦方面变化最大;有趣的是,所有组的疼痛减轻程度相当。跨测量的随访测试表明,早期(2至6个月)间隔变化更大,后期(6至12个月)间隔相对稳定。比较2至12个月内被归类为“改善者”与未改善者的情况,结果相似。许多首次发作背痛患者的临床病程可能会延长,并且涉及一系列相关的残疾和痛苦。首次背痛发作1年后有明显症状风险的个体可以早期识别,及时治疗可能会降低疼痛慢性化的风险。

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