Konrádová V, Uhlík J, Vajner L, Zocová J
Institute of Histology and Embryology, 2nd Faculty of Medicine, Charles University, Praha, Czech Republic.
Vet Med (Praha). 1997 Oct;42(10):289-93.
The ultrastructure of the rabbit tracheal epithelium was studied 30 minutes after intratracheal administration of two puffs of salbutamol and ipratropium bromide, respectively. The injury to the tracheal epithelium due to the treatment with both bronchospasmolytic drugs was considered moderate to severe. In both experimental groups, the degree of goblet cells' stimulation did not differ significantly, the ciliated cells were less damaged compared with the goblet ones and the morphological signs of the impaired self-cleaning ability were revealed.
分别经气管内给予两喷沙丁胺醇和异丙托溴铵30分钟后，对兔气管上皮的超微结构进行了研究。两种支气管解痉药物治疗导致的气管上皮损伤被认为是中度至重度。在两个实验组中，杯状细胞的刺激程度无显著差异，与杯状细胞相比，纤毛细胞受损较轻，且出现了自我清洁能力受损的形态学迹象。
