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[血液中免疫球蛋白水平与人类痢疾易感性之间的可能联系]

[The possible connection between immunoglobulin levels in the blood and human susceptibility to dysentery].

作者信息

Khazenson L B, Sholud'ko G S, Nikolaeva T A

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1976 May(5):89-94.

PMID:941610
Abstract

A determination was made of the immunoglobulin G, M and A concentration in the blood serum of women suffering from dysentery and other acute intestinal diseases, those who sustained the disease and healthy persons (259 in all). Probability of detection of low IgA concentrations in the patients was 7-12 times greater during the first days of the disease than in healthy persons; IgG And IgM levels in the patients who sustained the disease and in healthy individuals showed no significant difference. Possible relationship between the synthesis of the secretory IgA in the intestine and the blood serum IgA level was discussed; however, a conclusion on a possibility of detection of persons most susceptible to dysentery and other acute intestinal diseases by the low serum IgA level could be made only after further investigations.

摘要

对患有痢疾和其他急性肠道疾病的女性、患病康复者以及健康人(共259人)的血清中的免疫球蛋白G、M和A浓度进行了测定。患病初期患者检测到低IgA浓度的概率比健康人高7至12倍;患病康复者与健康个体的IgG和IgM水平无显著差异。文中讨论了肠道分泌型IgA合成与血清IgA水平之间可能存在的关系;然而,只有在进一步研究之后才能得出关于通过低血清IgA水平检测最易患痢疾和其他急性肠道疾病人群可能性的结论。

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Zh Mikrobiol Epidemiol Immunobiol. 1976 May(5):89-94.
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