Iushchuk N D, Kupkina G K
Zh Mikrobiol Epidemiol Immunobiol. 1977 Feb(2):90-4.
A study was made of 350 patients suffering from food toxinfections and dysentery; the quantitative variations in the Ig content were determined in the blood serum by Mancicni's method, depending on the period and the severity of the disease. A total of 768 investigations were conducted. Distinct shifts in the IgA and IgM were revealed in the patients with food poisoning and salmonellosis pursuing a moderately severe course; IgG content varied within the normal range during the whole observation period. At the acute period of dysentery the content of all the three immunoglobulin classes (both in the typical and atypical course of the process) displayed no significant differences from that in the healthy individuals; during the convalescence in typical and atypical (gastroenterocolitic) course of dysentery the Ig content constituted, respectively: IgA--292.0 +/- 11.5 and 387 +/- 14.1, IgM--84.8 +/- 3.1 and 104.0 +/- 8.0; Ig G--1500 +/- 38.0 and 1730.0 +/- 62.7.
对350例食物毒素感染和痢疾患者进行了研究；采用曼西尼法测定血清中免疫球蛋白（Ig）含量的定量变化，该变化取决于疾病的时期和严重程度。总共进行了768次检测。在病情呈中度严重的食物中毒和沙门氏菌病患者中，IgA和IgM出现明显变化；在整个观察期内，IgG含量在正常范围内波动。在痢疾急性期，所有三类免疫球蛋白的含量（无论是典型病程还是非典型病程）与健康个体相比均无显著差异；在典型和非典型（胃肠结肠型）痢疾病程的恢复期，Ig含量分别为：IgA——292.0±11.5和387±14.1，IgM——84.8±3.1和104.0±8.0；IgG——1500±38.0和1730.0±62.7。
