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[正常及免疫IgG、IgM和IgA对实验性菌群失调小鼠肠道微生物群的影响]

[Effect of normal and immune IgG, IgM and IgA on the intestinal microflora of mice with experimental dysbacteriosis].

作者信息

Glad'ko I A, Korshunov V M, Pinegin B V, Moshiashvili I Ia

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1985 Oct(10):60-3.

PMID:3911673
Abstract

Human IgG, IgM and IgA produce a pronounced protective effect, preventing enterobacteria from penetration into the mucous membrane of the proximal section of the small intestine of mice in antibiotic-induced dysbacteriosis. Normal mouse IgG and IgM, in contrast to IgA, are effective against mucosal enterobacteria of the small intestine. Immune mouse IgG, IgM and IgA show greater activity in protecting the mucous membrane than normal immunoglobulins of these classes.

摘要

人免疫球蛋白G、免疫球蛋白M和免疫球蛋白A产生显著的保护作用,可防止肠道杆菌在抗生素诱导的菌群失调小鼠的小肠近端黏膜中渗透。与免疫球蛋白A相比,正常小鼠的免疫球蛋白G和免疫球蛋白M对小肠黏膜肠道杆菌有效。免疫小鼠的免疫球蛋白G、免疫球蛋白M和免疫球蛋白A在保护黏膜方面比这些类别的正常免疫球蛋白表现出更强的活性。

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