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老年慢性精神分裂症患者适应性缺陷与认知缺陷之间的关联。

The association between adaptive and cognitive deficits in geriatric chronic schizophrenic patients.

作者信息

Harvey P D, Sukhodolsky D, Parrella M, White L, Davidson M

机构信息

Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA.

出版信息

Schizophr Res. 1997 Oct 30;27(2-3):211-8. doi: 10.1016/S0920-9964(97)00068-6.

Abstract

Cognitive impairments have been shown to predict impairments in adaptive functioning in patients with chronic schizophrenia and to be more predictive of overall outcome than positive or negative symptoms of the illness. Both adaptive and cognitive impairments are multidimensional, and it is possible that correlations between these domains may be limited to certain aspects of these functions. In this study, 208 geriatric patients with chronic schizophrenia were examined with a cognitive battery and assessed with a structured scale to determine the extent of their adaptive functions. Instrumental and social skills deficits were more strongly correlated with cognitive impairments than with the severity of undercontrolled behavior. Each of the cognitive measures was correlated with global social-adaptive deficits, with minimal variation in the magnitude of correlations. These results suggest that interventions should be individually targeted to cognitive-adaptive impairments and undercontrolled behavior.

摘要

认知障碍已被证明可预测慢性精神分裂症患者的适应性功能障碍,且比该疾病的阳性或阴性症状更能预测总体预后。适应性和认知障碍都是多维度的,这些领域之间的相关性可能仅限于这些功能的某些方面。在本研究中,对208名老年慢性精神分裂症患者进行了认知测试,并使用结构化量表进行评估,以确定其适应性功能的程度。工具性和社交技能缺陷与认知障碍的相关性比与行为控制不足的严重程度更强。每项认知测量都与整体社会适应性缺陷相关,相关性大小的变化最小。这些结果表明,干预措施应针对认知-适应性障碍和行为控制不足进行个体化。

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