Mazur M, Szmigielski A
Acta Physiol Pol. 1976 May-Jun;27(3):280-6.
Dopamine (DA) and noradrenaline (NA) levels and their turnover were determined in the rat brain after seven weeks of oral administration of ethanol and five or ten days after its withdrawal. No changes in DA and NA levels were found. Elevation of 14C-DA and 14C-NA accumulation and acceleration of 3H-DA disappearance were shown after prolonged ethanol administration. The effect of ethanol on NA turnover was much smaller than that on DA turnover. Five days after ethanol withdrawal no changes were found in DA and NA turnover. Five days later DA turnover was slightly slower than that in the control animals.
在大鼠口服乙醇七周后及其撤药五或十天后，测定其脑内多巴胺（DA）和去甲肾上腺素（NA）水平及其周转率。未发现DA和NA水平有变化。长期给予乙醇后，显示14C-DA和14C-NA蓄积增加，3H-DA消失加速。乙醇对NA周转率的影响远小于对DA周转率的影响。乙醇撤药五天后，DA和NA周转率未发现变化。五天后，DA周转率略慢于对照动物。
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