Shmarov D A, Kuchma Iu M, Kozinets G I
Klin Lab Diagn. 1997 Oct(10):3-5.
The distribution of bone marrow cells by stages of cell cycle was studied by flow cytometry in 26 normal subjects and 107 adult patients (42 with anemias and 65 with acute lymphoblastic or myeloblastic leukemias). Normal myelokaryocyte cell cycle is rather stable, which manifests by low variability of cells. In anemias and, more so, in leukemias the proliferative status of cells varies within a wide range, which is explained by unstable and ineffective hemopoiesis.
通过流式细胞术研究了26名正常受试者和107名成年患者(42名贫血患者和65名急性淋巴细胞白血病或急性髓细胞白血病患者)骨髓细胞的细胞周期阶段分布。正常骨髓细胞的细胞周期相当稳定,表现为细胞变异性低。在贫血患者中,尤其是白血病患者中,细胞的增殖状态在很大范围内变化,这是由于造血不稳定和无效所致。