Ferguson B B, Wilson D J, Schaffner W
Am J Dis Child. 1976 Aug;130(8):837-9. doi: 10.1001/archpedi.1976.02120090047008.
A total of 34 samples of human milk from 15 donors was analyzed for nicotine content, using a new method of sample preparation and subsequent quantification by gas chromatography. Nicotine was not found in the six samples of milk from non-smokers. The 28 samples from smokers contained an average of 91 parts per billion (ppb) nicotine (ranging from less than 20 ppb to 512 ppb). While no adverse effects to the infant due to nicotine in human milk have been documented, this method of analysis will allow systematic monitoring of nicotine concentrations in the milk of lactating women. These results should not be used to deter breast-feeding; rather, they offer another reason for mothers to reduce or cease smoking.
采用一种新的样品制备方法并随后通过气相色谱法定量，对来自15名捐赠者的34份母乳样本进行了尼古丁含量分析。在6份非吸烟者的母乳样本中未发现尼古丁。28份吸烟者的母乳样本中尼古丁平均含量为十亿分之91（ppb）（范围从低于20 ppb到512 ppb）。虽然尚未有文献记载母乳中的尼古丁会对婴儿产生不良影响，但这种分析方法将有助于对哺乳期妇女乳汁中的尼古丁浓度进行系统监测。这些结果不应被用于劝阻母乳喂养；相反，它们为母亲减少或戒烟提供了另一个理由。
