先天性唇裂与波动性皮纹不对称。
Congenital cleft lip and fluctuating dermatoglyphic asymmetry.
作者信息
Woolf C M, Gianas A D
出版信息
Am J Hum Genet. 1976 Jul;28(4):400-3.
Abstract
Fluctuating asymmetry for the palmar atd angle was studied in propositi born with CL(P) and their normal parents and sibs. The propositi with a family history of this congenital malformation were significantly different from the controls for this type of asymmetry. The propositi without a family history and the normal parents and sibs of both types of propositi were similar to the controls. The difference between the two types of propositi suggests that in some individuals a genetic mechanism may account for CL(P) and increased fluctuating asymmetry for this dermatoglyphic trait.
摘要
对患有先天性唇腭裂（CL(P)）的研究对象及其正常父母和兄弟姐妹的手掌atd角的波动不对称性进行了研究。有这种先天性畸形家族史的研究对象在这种不对称类型上与对照组有显著差异。没有家族史的研究对象以及两类研究对象的正常父母和兄弟姐妹与对照组相似。两类研究对象之间的差异表明，在某些个体中，一种遗传机制可能导致先天性唇腭裂（CL(P)）以及这种皮纹特征的波动不对称性增加。
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