Verkasalo P K, Kaprio J, Varjonen J, Romanov K, Heikkilä K, Koskenvuo M
Department of Public Health, University of Helsinki, Finland.
Am J Epidemiol. 1997 Dec 15;146(12):1037-45. doi: 10.1093/oxfordjournals.aje.a009232.
Electromagnetic fields have been suggested to contribute to the risk of depression by causing pineal dysfunction. Some epidemiologic studies have supported this possibility but have generally reported crude methods of exposure assessment and nonsystematic evaluation of depression. Using two available nationwide data sets, the authors identified from the Finnish Twin Cohort Study 12,063 persons who had answered the 21-item Beck Depression Inventory of self-rated depressive symptoms in 1990. The personal 20-year histories of exposure (i.e., distance and calculated annual average magnetic fields) before 1990 to overhead 110- to 400-kv power lines were obtained from the Finnish Transmission Line Cohort Study. The adjusted mean Beck Depression Inventory scores did not differ by exposure, providing some assurance that proximity to high-voltage transmission lines is not associated with changes within the common range of depressive symptoms. However, the risk of severe depression was increased 4.7-fold (95% confidence interval 1.70-13.3) among subjects living within 100 m of a high-voltage power line. This finding was based on small numbers. The authors recommend that attempts be made to strive for a better understanding of the exposure characteristics in relation to the onset and course of depression.
电磁场被认为可通过引起松果体功能障碍而增加患抑郁症的风险。一些流行病学研究支持了这种可能性，但通常报告的是粗略的暴露评估方法以及对抑郁症的非系统性评估。作者利用两个现有的全国性数据集，从芬兰双胞胎队列研究中识别出12,063名在1990年回答了包含21个条目的贝克抑郁自评量表的人。1990年之前个人接触110至400千伏架空输电线的20年暴露史（即距离和计算得出的年平均磁场）来自芬兰输电线队列研究。经调整后的贝克抑郁自评量表平均得分并未因暴露情况而有所不同，这为接近高压输电线与常见抑郁症状范围内的变化无关提供了一定保证。然而，居住在距高压电线100米范围内的受试者中，重度抑郁症的风险增加了4.7倍（95%置信区间为1.70至13.3）。这一发现基于少数样本。作者建议努力更好地了解与抑郁症发病和病程相关的暴露特征。
