Nanni C A, Alster T S
Washington Institute of Dermatologic Laser Surgery, Washington, DC 20037, USA.
Arch Dermatol. 1997 Dec;133(12):1546-9.
To determine the most effective treatment parameters for laser-assisted hair removal using a Q-switched neodymium:yttrium-aluminum-garnet (Nd:YAG) laser.
Prospective study to determine the effectiveness of Q-switched ND:YAG laser-assisted hair removal under varying pretreatment protocols. Hair growth was assessed after laser treatment, and the results were compared with those of wax epilation at 4, 12, and 24 weeks.
A private ambulatory laser facility and academic referral center.
Laser-assisted hair removal was performed under 4 different pretreatment conditions. Eighteen areas of unwanted body and facial hair from 12 study subjects were divided into 4 quadrants. Wax epilation followed by application of a carbon-based solution and exposure to Q-switched Nd:YAG laser radiation was performed on 1 quadrant. A second quadrant was wax epilated and exposed to Q-switched Nd:YAG laser radiation without prior carbon solution application. A third quadrant was exposed to laser radiation alone, and a final quadrant was wax epilated to serve as the control. Follow-up evaluations at 1, 3, and 6 months consisted of photographic documentation, manual hair counts, and patient hair-density estimates.
Percentage of hair regrowth as assessed by objective hair counts and patient subjective evaluations.
Mean percentage of hair regrowth at 1 month was 39.9% for the wax-carbon-laser quadrant, 46.7% for the wax-laser quadrant, 66.1% for the laser-alone quadrant, and 77.9% for the wax control quadrant. The percentage of hair regrowth approximately doubled by 3 months but was significantly delayed in all laser-treated quadrants regardless of pretreatment protocol. Full hair regrowth in all anatomic locations was observed by month 6. Patient subjective evaluations of hair density closely approximated hair count data. No adverse effects or long-term complications were observed.
A single hair-removal treatment with the Q-switched Nd:YAG laser is safe and effective in delaying hair growth for up to 3 months. Although the combination of pretreatment wax epilation and topical carbon solution application was effective, laser irradiation alone, with or without wax epilation, also provided a significant delay in hair growth.
确定使用调Q钕：钇铝石榴石（Nd：YAG）激光进行激光辅助脱毛的最有效治疗参数。
前瞻性研究，以确定在不同预处理方案下调Q Nd：YAG激光辅助脱毛的有效性。在激光治疗后评估毛发生长情况，并在4周、12周和24周时将结果与蜡脱毛的结果进行比较。
一家私立门诊激光机构和学术转诊中心。
在4种不同的预处理条件下进行激光辅助脱毛。将12名研究对象身上18处不需要的身体和面部毛发区域分为4个象限。在1个象限进行蜡脱毛，然后涂抹碳基溶液并接受调Q Nd：YAG激光照射。在第二个象限进行蜡脱毛并接受调Q Nd：YAG激光照射，事先不涂抹碳溶液。在第三个象限单独接受激光照射，最后一个象限进行蜡脱毛作为对照。在1个月、3个月和6个月时的随访评估包括拍照记录、手动计数毛发以及患者对毛发密度的估计。
通过客观的毛发计数和患者主观评估来评估毛发再生的百分比。
1个月时，蜡 - 碳 - 激光象限的毛发再生平均百分比为39.9%，蜡 - 激光象限为46.7%，仅激光象限为66.1%，蜡对照象限为77.9%。到3个月时，毛发再生百分比大约翻倍，但无论预处理方案如何，所有激光治疗象限的毛发再生都明显延迟。到6个月时，在所有解剖部位都观察到毛发完全再生。患者对毛发密度的主观评估与毛发计数数据非常接近。未观察到不良反应或长期并发症。
单次使用调Q Nd：YAG激光进行脱毛治疗在延迟毛发生长方面安全有效，长达3个月。虽然预处理蜡脱毛和局部涂抹碳溶液的联合方法有效，但单独进行激光照射，无论是否进行蜡脱毛，也能显著延迟毛发生长。
