Driesens R J
J Clin Microbiol. 1976 Aug;2(2):85-8.
Vaccines made from the Ty-2 strain of Salmonella typhosa were tested periodically for stability of pH and of potency. The acetone-treated cultures prepared in buffered saline solutions retained potency beyond 30 months of storage at 0 to 5 C. Similar vaccines in unbuffered saline solutions lost potency coincident with increase of alkalinity. Vaccines packaged in United States Pharmacopeia borosilicate glass vials retained potency and pH stability, whereas those in Type III United States Pharmacopeia soda-lime glass vials were less stable.
对由伤寒沙门氏菌Ty-2菌株制成的疫苗进行了pH值和效力稳定性的定期测试。在缓冲盐溶液中制备的经丙酮处理的培养物在0至5摄氏度下储存超过30个月后仍保持效力。在无缓冲盐溶液中的类似疫苗随着碱度的增加而失去效力。包装在美国药典硼硅酸盐玻璃瓶中的疫苗保持了效力和pH稳定性，而包装在美国药典III型钠钙玻璃瓶中的疫苗则稳定性较差。
