使用新型吸附过滤器Biofil P 10 BBS对单供体血小板制剂进行白细胞去除
White blood cell depletion of single-donor platelet preparations using the new adsorption filter biofil P 10 BBS.
作者信息
Müller N
机构信息
Institute of Transfusion Medicine, University Clinics Essen, Germany.
出版信息
Beitr Infusionsther Transfusionsmed. 1994;32:55-7.
A newly developed adsorption filter has been evaluated for the removal of white blood cells (WBC) from platelet concentrates obtained by the blood cell separators Fenwal CS 3000 Plus (CS) and Haemonetics PCS Plus (H). WBC mean removal rate was 99.82 +/- 0.21% (H) and 99.58 +/- 0.01% (CS) with a mean WBC yield of (13.68 +/- 21.52) x 10(5) (H) and (0.20 +/- 0.23) x 10(5) (CS). Platelet recovery was 86.11 +/- 6.74% (H) and 83.04 +/- 5.59% (CS). Morphology, integrity and in vitro function parameters were not influenced by the filtration.
一种新开发的吸附过滤器已被评估用于从血细胞分离机Fenwal CS 3000 Plus（CS）和Haemonetics PCS Plus（H）获得的血小板浓缩物中去除白细胞（WBC）。白细胞平均去除率为99.82±0.21%（H）和99.58±0.01%（CS），平均白细胞回收率为（13.68±21.52）×10⁵（H）和（0.20±0.23）×10⁵（CS）。血小板回收率为86.11±6.74%（H）和83.04±5.59%（CS）。形态、完整性和体外功能参数不受过滤影响。
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