大鼠肝细胞核中与染色质结合及游离形式的聚腺苷酸聚合酶
Chromatin-bound and free forms of poly(adenylic acid) polymerase in rat hepatic nuclei.
作者信息
Jacob S T, Roe F J, Rose K M
出版信息
Biochem J. 1976 Mar 1;153(3):733-5. doi: 10.1042/bj1530733.
Abstract
Isolated rat hepatic nuclei were shown to contain poly(A) polymerase in two distinct physiologically active forms. One form was associated with the chromatin fraction and was dependent on endogenous RNA, presumably mRNA. The other activity was localized in the nuclear sap in a 'free' form and was stimulated almost 30-40-fold by exogenously added poly(A). Isolated nucleoli were devoid of significant poly(A)-synthesizing activity.
摘要
已证明分离出的大鼠肝细胞核含有两种不同生理活性形式的聚腺苷酸聚合酶。一种形式与染色质部分相关，并且依赖于内源性RNA，推测为信使核糖核酸（mRNA）。另一种活性以“游离”形式定位于核液中，并且被外源添加的聚腺苷酸刺激了近30 - 40倍。分离出的核仁没有显著的聚腺苷酸合成活性。
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2
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Cancer Res. 1967 Jan;27(1):52-60.
3
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Biochemistry. 1969 Apr;8(4):1698-706. doi: 10.1021/bi00832a053.
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