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Chromatin-bound and free forms of poly(adenylic acid) polymerase in rat hepatic nuclei.大鼠肝细胞核中与染色质结合及游离形式的聚腺苷酸聚合酶
Biochem J. 1976 Mar 1;153(3):733-5. doi: 10.1042/bj1530733.
2
[Circadian rhythm of poly A polymerase in chromatin and nucleoplasmatic extract of rat liver].[大鼠肝脏染色质和核质提取物中多聚腺苷酸聚合酶的昼夜节律]
Ateneo Parmense Acta Biomed. 1979;50(1):55-8.
3
Phosphorylation of nuclear poly(adenylic acid) polymerase by protein kinase: mechanism of enhanced poly(adenylic acid) synthesis.蛋白激酶对核聚腺苷酸聚合酶的磷酸化作用：聚腺苷酸合成增强的机制
Biochemistry. 1980 Apr 1;19(7):1472-6. doi: 10.1021/bi00548a033.
4
[Effect of administration of alpha-amanitine on Mn2+ - dependent poly-A-polymerase in rat liver nuclei].[α-鹅膏蕈碱给药对大鼠肝细胞核中锰离子依赖性多聚腺苷酸聚合酶的影响]
Ateneo Parmense Acta Biomed. 1979;50(1):93-5.
5
[Circadian rhythm of poly A polymerase in rat liver nuclei].[大鼠肝细胞核中多聚腺苷酸聚合酶的昼夜节律]
Ateneo Parmense Acta Biomed. 1979;50(1):35-8.
6
Poly(adenylic acid) polymerase: loss of enzyme from rat liver nuclei isolated under isotonic conditions.聚腺苷酸聚合酶：在等渗条件下分离的大鼠肝细胞核中该酶的缺失
FEBS Lett. 1976 Aug 15;67(2):193-7. doi: 10.1016/0014-5793(76)80364-x.
7
[Nuclear and cytoplasmic Mn++ and Mg++ dependent poly(A) polymerase activities in rat liver].[大鼠肝脏中依赖核与细胞质的锰离子和镁离子的聚腺苷酸聚合酶活性]
Boll Soc Ital Biol Sper. 1975 Sep 30;51(18):1113-9.
8
Response of poly(adenylic acid) polymerase in rat liver nuclei and mitochondria to stravation and re-feeding with amino acids.大鼠肝脏细胞核和线粒体中聚腺苷酸聚合酶对饥饿及氨基酸再喂养的反应。
Biochem J. 1976 Aug 15;158(2):161-7. doi: 10.1042/bj1580161.
9
Androgen regulation of nuclear poly(A) polymerase activities in rat ventral prostate.雄激素对大鼠腹侧前列腺中核聚腺苷酸聚合酶活性的调节
Biochim Biophys Acta. 1983 Oct 18;760(2):278-82. doi: 10.1016/0304-4165(83)90174-5.
10
Thyroid hormone regulation of poly(adenylate) polymerase activities in neuronal nuclei of developing rat brain cortex.甲状腺激素对发育中大鼠大脑皮质神经元细胞核中聚腺苷酸聚合酶活性的调节
Biochem Biophys Res Commun. 1984 Dec 28;125(3):931-7. doi: 10.1016/0006-291x(84)91373-1.

引用本文的文献

1
Effect of tryptophan on rat hepatic nuclear poly(A)polymerase activity.色氨酸对大鼠肝细胞核多（A）聚合酶活性的影响。
Amino Acids. 1993 Jun;5(2):263-71. doi: 10.1007/BF00805989.

本文引用的文献

1
Isolation of nucleoli in a medium containing spermine and magnesium acetate.在含有精胺和醋酸镁的培养基中分离核仁。
Exp Cell Res. 1967 Aug;47(1):329-36. doi: 10.1016/0014-4827(67)90235-2.
2
Turnover of 45 S RNA of regenerating liver and Walker tumor.再生肝和沃克癌瘤中45S RNA的周转
Cancer Res. 1967 Jan;27(1):52-60.
3
Studies on nuclear exoribonucleases. 3. Isolation and properties of the enzyme from normal and malignant tissues of the mouse.核糖核酸外切酶研究。3. 从小鼠正常组织和恶性组织中分离该酶及其性质
Biochemistry. 1969 Apr;8(4):1698-706. doi: 10.1021/bi00832a053.
4
Polyriboadenylate polymerase solubilized from rat liver mitochondria.从大鼠肝脏线粒体中溶解出来的聚腺苷酸聚合酶。
Biochem Biophys Res Commun. 1972 Jul 11;48(1):126-34. doi: 10.1016/0006-291x(72)90353-1.
5
State of adenovirus 2 deoxyribonucleic acid in the nucleus and its mode of transcription: studies with isolated viral deoxyribonucleic acid-protein complexes and isolated nuclei.腺病毒2型脱氧核糖核酸在细胞核中的状态及其转录模式：对分离的病毒脱氧核糖核酸-蛋白质复合物和分离细胞核的研究
J Virol. 1972 Apr;9(4):627-35. doi: 10.1128/JVI.9.4.627-635.1972.
6
A poly(A) polymerase from calf thymus. Purification and properities of the enzyme.来自小牛胸腺的聚腺苷酸聚合酶。该酶的纯化及特性
J Biol Chem. 1973 Jul 10;248(13):4756-62.
7
Eukaryotic messenger RNA.真核生物信使核糖核酸
Annu Rev Biochem. 1974;43(0):621-42. doi: 10.1146/annurev.bi.43.070174.003201.
8
A poly(A) polymerase from calf thymus. Characterization of the reaction product and the primer requirement.来自小牛胸腺的聚腺苷酸聚合酶。反应产物的特性及对引物的需求
J Biol Chem. 1973 Jul 10;248(13):4763-8.
9
Ribosomal RNA synthesis in isolated nuclei.分离细胞核中的核糖体RNA合成。
J Mol Biol. 1972 Jun 28;67(3):433-41. doi: 10.1016/0022-2836(72)90461-5.
10
The in vitro synthesis of avian myeloblastosis viral RNA sequences.禽成髓细胞瘤病毒RNA序列的体外合成
Proc Natl Acad Sci U S A. 1974 Aug;71(8):3045-9. doi: 10.1073/pnas.71.8.3045.

大鼠肝细胞核中与染色质结合及游离形式的聚腺苷酸聚合酶

Chromatin-bound and free forms of poly(adenylic acid) polymerase in rat hepatic nuclei.

作者信息

Jacob S T, Roe F J, Rose K M

出版信息

Biochem J. 1976 Mar 1;153(3):733-5. doi: 10.1042/bj1530733.

DOI:10.1042/bj1530733
PMID:942385
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1172644/
Abstract

Isolated rat hepatic nuclei were shown to contain poly(A) polymerase in two distinct physiologically active forms. One form was associated with the chromatin fraction and was dependent on endogenous RNA, presumably mRNA. The other activity was localized in the nuclear sap in a 'free' form and was stimulated almost 30-40-fold by exogenously added poly(A). Isolated nucleoli were devoid of significant poly(A)-synthesizing activity.

摘要

已证明分离出的大鼠肝细胞核含有两种不同生理活性形式的聚腺苷酸聚合酶。一种形式与染色质部分相关，并且依赖于内源性RNA，推测为信使核糖核酸（mRNA）。另一种活性以“游离”形式定位于核液中，并且被外源添加的聚腺苷酸刺激了近30 - 40倍。分离出的核仁没有显著的聚腺苷酸合成活性。