Lipid metabolism in cultured aortic smooth muscle cells and comparison with other cell types. Part I. Composition of cells grown in hyperlipemic serum.

The lipid compositions of cultured rabbit aortic smooth muscle cells, adventitial fibroblasts and skin fibroblasts were determined for cells grown in media containing either normolipemic or hyperlipemic serum. No significant changes were found in cell phospholipid composition. Each of the threee cell types responded similarly to hyperlipemic serum, accumulating esterified cholesterol and triglyerides.