Jeng O J, Radwin R G, Moore J S, Roberts M, Garrity J M, Oswald T
New Jersey Institute of Technology, Newark 07102, USA.
Am Ind Hyg Assoc J. 1997 Dec;58(12):885-92. doi: 10.1080/15428119791012234.
This study evaluated the Wisconsin functional sensory and psychomotor test battery for carpal tunnel syndrome (CTS). Subjects were 27 employees recruited from a food processing plant. Both hands of all subjects were examined and categorized by presence or absence of symptoms and nerve conduction study (NCS) findings (Symptom-/NCS-, Symptom+/NCS-, Symptom-/NCS+, and Symptom+/NCS+). Symptom-/NCS- category hands had significantly better performance (15-60%) for most of the functional test battery variables than Symptom+/NCS+ category hands. A significant gap detection threshold difference (32%) was observed between NCS+ and NCS- hands regardless of symptoms, with NCS- having impaired performance. No significant effect of CTS symptoms on performance was observed. Stepwise discriminant analysis was used to select the best variables to differentiate between groups. The ratio of the change in pinch rate with respect to required pinch force differentiated NCS+ from NCS- hands, with a sensitivity of 0.71 and a specificity of 0.68. The same variable had a sensitivity of 0.74 and specificity of 0.83 for distinguishing Symptom-/NCS- hands from all other categories. Pinch rate had a sensitivity of 0.82 and a specificity of 0.81 for separating Symptom+/NCS+ hands from all other categories. Use of both gap detection threshold and the ratio of the change in pinch rate with respect to required pinch force could best differentiate Symptom+/NCS+ from Symptom-/NCS- cases for a sensitivity of 0.91 and specificity of 0.87. Outcomes could not be generalized to a specific work population but demonstrate that the non-invasive test battery may be useful for providing objective measures of deficits associated with CTS symptoms and electrophysiological parameters.
本研究评估了用于腕管综合征（CTS）的威斯康星功能感觉和心理运动测试组套。研究对象为从一家食品加工厂招募的27名员工。对所有研究对象的双手进行检查，并根据是否存在症状和神经传导研究（NCS）结果进行分类（无症状/NCS正常、有症状/NCS正常、无症状/NCS异常、有症状/NCS异常）。在大多数功能测试组套变量方面，无症状/NCS正常组的手部表现明显更好（高出15 - 60%），优于有症状/NCS异常组。无论有无症状，NCS异常组和NCS正常组的手部之间均观察到显著的缺口检测阈值差异（32%），NCS异常组的表现受损。未观察到CTS症状对表现有显著影响。采用逐步判别分析来选择区分不同组别的最佳变量。捏力变化率与所需捏力的比值能够区分NCS异常组和NCS正常组的手部，敏感性为0.71，特异性为0.68。对于区分无症状/NCS正常组与所有其他类别，同一变量的敏感性为0.74，特异性为0.83。捏力变化率区分有症状/NCS异常组与所有其他类别时，敏感性为0.82，特异性为0.81。同时使用缺口检测阈值和捏力变化率与所需捏力的比值，能够最佳地区分有症状/NCS异常组和无症状/NCS正常组，敏感性为0.91，特异性为0.87。研究结果不能推广到特定的工作人群，但表明该非侵入性测试组套可能有助于提供与CTS症状和电生理参数相关的功能缺陷的客观测量指标。
