Jeng O J, Radwin R G, Fryback D G
New Jersey Institute of Technology, Newark 07102, USA.
Am Ind Hyg Assoc J. 1997 Dec;58(12):852-60. doi: 10.1080/15428119791012180.
Two new computer-controlled functional tests were developed, known as the Wisconsin test battery, for carpal tunnel syndrome (CTS). The gap detection sensory test quantifies tactile thresholds for areas of the hand innervated by the median nerve. The rapid pinch and release psychomotor test measures the initiation and control of specific muscles innervated by the median nerve motor branch. Ten confirmed CTS patients (based on electrophysiological parameters and examination; 18 CTS hands) and eight confirmed normal subjects (16 hands) with a similar average age were administered both tests. The CTS patients showed significant functional deficits for both tactility and psychomotor tests. Average CTS performance was 24 to 104% poorer than for the normal subjects, depending on the performance measure. The results indicated high correlations (r = 0.5 to 0.8) between median nerve electrophysiological parameters and tactility or psychomotor performance variables. No single functional test variable had sufficient sensitivity for detecting CTS among the subject pool. The combination of the two tests using 95% confidence level cutoff points achieved a sensitivity of 0.78 and a specificity of 0.81. Stepwise discriminant analysis resulted in two performance variables capable of a sensitivity of 0.72 and a specificity of 0.94 for differentiating well-defined CTS subjects from normal subjects. Despite these promising results, limitations of the study include small sample size and subject selection bias. Further studies are needed for verifying the utility of the functional test battery for detecting CTS in a general population.
针对腕管综合征（CTS），开发了两种新的计算机控制功能测试，即威斯康星测试组。间隙检测感觉测试可量化正中神经支配手部区域的触觉阈值。快速捏放心理运动测试可测量正中神经运动分支支配的特定肌肉的启动和控制能力。对10名确诊的CTS患者（基于电生理参数和检查；18只CTS手）和8名平均年龄相近的确诊正常受试者（16只手）进行了这两种测试。CTS患者在触觉和心理运动测试中均表现出明显的功能缺陷。根据性能指标，CTS患者的平均表现比正常受试者差24%至104%。结果表明，正中神经电生理参数与触觉或心理运动性能变量之间存在高度相关性（r = 0.5至0.8）。在受试人群中，没有单一的功能测试变量对检测CTS具有足够的敏感性。使用95%置信水平截止点的两种测试组合，敏感性为0.78，特异性为0.81。逐步判别分析得出两个性能变量，能够以0.72的敏感性和0.94的特异性将明确的CTS受试者与正常受试者区分开来。尽管有这些令人鼓舞的结果，但该研究的局限性包括样本量小和受试者选择偏差。需要进一步研究以验证功能测试组在普通人群中检测CTS的效用。
