Han T S, Kelly I E, Walsh K, Greene R M, Lean M E
University Department of Human Nutrition, Glasgow Royal Infirmary, UK.
Int J Obes Relat Metab Disord. 1997 Dec;21(12):1161-6. doi: 10.1038/sj.ijo.0800530.
To determine the level of a single transverse scan of intra-abdominal fat between L1 and L5 vertebrae that best predicts intra-abdominal fat volumes.
Sixteen male and seven female patients with non-insulin-dependent diabetes mellitus, aged 44-74 y.
Volumes and areas from single scans of intra-abdominal fat measured by magnetic resonance imaging with a 1.5 Tesla magnetic field strength.
Intra-abdominal fat volumes and were calculated from fat areas from eight cross-sectional transverse single scans (nine scans in eight men) of 20 mm thickness. Men and women, respectively, had mean body mass index (BMI) of 27.9 (s.d. 3.0) and 31.6 (s.d. 4.7) kg/m2, and intra-abdominal fat of 2.3 (s.d. 0.5) and 2.5 (s.d. 0.6) kg. Intra-abdominal fat area of the fourth scan (in the direction of L1 to L5) gave the highest prediction of total intra-abdominal fat both in men (r = 0.959, P < 0.001) and in women (r = 0.973, P < 0.001). The intra-abdominal fat area of the third scan gave almost as good a prediction. These third and fourth scans corresponded to L2 and L3 vertebrae. The intra-abdominal fat areas from the sixth and seventh scans, corresponded to the frequently used L4-L5 and had lower correlations with intra-abdominal fat. There were no gender differences in the prediction of volumes from areas of intra-abdominal fat. Intra-abdominal fat areas of the fourth scan explained 93% of variance (SEE = 0.14 kg) of total of intra-abdominal fat for both genders: intra-abdominal fat (kg) = 0.0108 x intra-abdominal fat area of the fourth scan (cm2) + 0.244.
In large studies of intra-abdominal fat, using magnetic resonance imaging (MRI) or computerised tomography scanning, a single intra-abdominal fat area at the intervertebral disc between L-2 and L-3 vertebrae offers a cheaper, faster and safer method, with high prediction of total intra-abdominal fat volumes and masses.
确定在L1和L5椎体之间进行单次腹部横断面扫描时，能最佳预测腹部脂肪体积的层面。
16名男性和7名女性非胰岛素依赖型糖尿病患者，年龄44 - 74岁。
采用1.5特斯拉磁场强度的磁共振成像测量单次腹部脂肪扫描的体积和面积。
腹部脂肪体积由20毫米厚的8个横断面单次扫描（8名男性为9次扫描）的脂肪面积计算得出。男性和女性的平均体重指数（BMI）分别为27.9（标准差3.0）和31.6（标准差4.7）kg/m²，腹部脂肪分别为2.3（标准差0.5）和2.5（标准差0.6）kg。第四次扫描（沿L1至L5方向）的腹部脂肪面积对男性（r = 0.959，P < 0.001）和女性（r = 0.973，P < 0.001）的腹部总脂肪预测值最高。第三次扫描的腹部脂肪面积预测效果几乎相同。这些第三次和第四次扫描对应于L2和L3椎体。第六次和第七次扫描的腹部脂肪面积对应于常用的L4 - L5，与腹部脂肪的相关性较低。腹部脂肪面积对脂肪体积的预测不存在性别差异。第四次扫描的腹部脂肪面积解释了两性腹部总脂肪93%的方差（标准误 = 0.14 kg）：腹部脂肪（kg）= 0.0108×第四次扫描的腹部脂肪面积（cm²）+ 0.244。
在使用磁共振成像（MRI）或计算机断层扫描的大型腹部脂肪研究中，L2和L3椎体之间椎间盘处的单次腹部脂肪面积提供了一种更便宜、更快且更安全的方法，对腹部总脂肪体积和质量具有较高的预测性。
