Rodríguez A D, Cóbar O M, Padilla O L, Barnes C L
Department of Chemistry, University of Puerto Rico, Río Piedras 00931-3346, USA.
J Nat Prod. 1997 Dec;60(12):1331-3. doi: 10.1021/np970328e.
Calyxamines A (1) and B (2) are 2,2,4,6,6-pentasubstituted piperidine alkaloids possessing novel carbon skeletons isolated from the marine sponge Calyx podatypa collected in Puerto Rico. Their structures, after derivatization with trifluoroacetic acid, have been determined by a combination of X-ray and spectroscopic methods. A plausible biogenetic pathway to the calyxamines is suggested.
萼胺A（1）和B（2）是从在波多黎各采集的海洋海绵萼状多孔螅中分离得到的具有新型碳骨架的2,2,4,6,6-五取代哌啶生物碱。在用三氟乙酸衍生化后，它们的结构已通过X射线和光谱方法相结合得以确定。文中还提出了一条关于萼胺的合理生源合成途径。
