Winn R J, Botnick W Z
Community Oncology Program, UT M.D. Anderson Cancer Center, Houston, USA.
Oncology (Williston Park). 1997 Nov;11(11A):25-32.
The goal of the National Comprehensive Cancer Network (NCCN) in developing clinical practice guidelines is to provide oncologists with guidance in making difficult clinical decisions. Since the data to make evidence-based decisions are often unavailable, the NCCN method attempts to integrate expert opinion into the process, striving to use that opinion in the most unbiased and reasonable manner through the diversity of its panels and the use of reiterative feedback loops. The development of oncology guidelines is a dynamic process. Each year the NCCN anticipates that the expert opinion elements of the guidelines will either be validated by clinical trial evidence or replaced by newer, sounder approaches.
美国国立综合癌症网络（NCCN）制定临床实践指南的目标是为肿瘤学家在做出艰难的临床决策时提供指导。由于做出循证决策所需的数据往往难以获取，NCCN的方法试图将专家意见纳入这一过程，通过其小组的多样性和反复反馈循环的使用，力求以最公正、合理的方式运用该意见。肿瘤学指南的制定是一个动态过程。NCCN预计，每年指南中的专家意见部分要么会被临床试验证据所验证，要么会被更新、更合理的方法所取代。
