• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Use of a gastric juice-based PCR assay to detect Helicobacter pylori infection in culture-negative patients.使用基于胃液的聚合酶链反应检测培养阴性患者的幽门螺杆菌感染。
J Clin Microbiol. 1998 Jan;36(1):317-20. doi: 10.1128/JCM.36.1.317-320.1998.
2
Detection of Helicobacter pylori DNA in gastric juice by the polymerase chain reaction: comparison with findings in bacterial culture and the detection of tissue IgA and serum IgG antibodies against Helicobacter pylori.通过聚合酶链反应检测胃液中的幽门螺杆菌DNA：与细菌培养结果以及针对幽门螺杆菌的组织IgA和血清IgG抗体检测结果的比较。
J Gastroenterol. 1995 Dec;30(6):689-95. doi: 10.1007/BF02349633.
3
Gastric juice polymerase chain reaction: an alternative to histology in the diagnosis of Helicobacter pylori infection.胃液聚合酶链反应：幽门螺杆菌感染诊断中组织学检查的替代方法
Helicobacter. 1996 Sep;1(3):159-64. doi: 10.1111/j.1523-5378.1996.tb00031.x.
4
Clinical usefulness of culturing H. pylori from gastric juice in patients with severe neurological impairment.
J Pediatr Gastroenterol Nutr. 2004 Oct;39(4):392-4. doi: 10.1097/00005176-200410000-00016.
5
Gastric juice urease test and brushing urease test for Helicobacter pylori detection.用于检测幽门螺杆菌的胃液尿素酶试验和刷检尿素酶试验。
J Med Assoc Thai. 2002 Jun;85 Suppl 1:S74-8.
6
Association of Helicobacter pylori cagA Gene with Gastric Cancer and Peptic Ulcer in Saudi Patients.沙特患者中幽门螺杆菌cagA基因与胃癌及消化性溃疡的关联
J Microbiol Biotechnol. 2015 Jul;25(7):1146-53. doi: 10.4014/jmb.1501.01099.
7
Gastric juice-based PCR assay: An alternative testing method to aid in the management of previously treated Helicobacter pylori infection.基于胃液的 PCR 检测：一种辅助治疗既往治疗过的幽门螺杆菌感染的替代检测方法。
Helicobacter. 2019 Apr;24(2):e12568. doi: 10.1111/hel.12568. Epub 2019 Feb 28.
8
Diagnosis and genotyping of Helicobacter pylori by polymerase chain reaction of bacterial DNA from gastric juice.通过对胃液中细菌DNA进行聚合酶链反应来诊断幽门螺杆菌并进行基因分型。
J Gastroenterol Hepatol. 2005 Aug;20(8):1253-9. doi: 10.1111/j.1440-1746.2005.03811.x.
9
Detection of antibody in serum and secretion for the diagnosis of Helicobacter pylori infection.检测血清和分泌物中的抗体以诊断幽门螺杆菌感染。
J Med Assoc Thai. 2002 Jun;85 Suppl 1:S383-8.
10
Diagnosis of Helicobacter pylori infection by means of a polymerase chain reaction assay for gastric juice aspirates.通过聚合酶链反应检测胃液抽吸物诊断幽门螺杆菌感染
Clin Infect Dis. 1993 Mar;16(3):367-71. doi: 10.1093/clind/16.3.367.

引用本文的文献

1
Detection of genotypic clarithromycin-resistant Helicobacter pylori by string tests.通过串珠试验检测基因型克拉霉素耐药性幽门螺杆菌
World J Gastroenterol. 2014 Mar 28;20(12):3343-9. doi: 10.3748/wjg.v20.i12.3343.
2
Use of the noninvasive entero-test in the detection of Helicobacter pylori in children in an endemic area in Colombia.在哥伦比亚流行地区使用非侵入性肠道测试来检测儿童中的幽门螺杆菌。
J Pediatr Gastroenterol Nutr. 2013 Aug;57(2):192-6. doi: 10.1097/MPG.0b013e318293e1e1.
3
Helicobacter pylori virulence genes detected by string PCR in children from an urban community in northeastern Brazil.巴西东北部一城市社区儿童中通过串珠聚合酶链反应检测到的幽门螺杆菌毒力基因。
J Clin Microbiol. 2013 Mar;51(3):988-9. doi: 10.1128/JCM.02583-12. Epub 2012 Dec 19.
4
Gastric juice for the diagnosis of H pylori infection in patients on proton pump inhibitors.用于诊断使用质子泵抑制剂患者幽门螺杆菌感染的胃液
World J Gastroenterol. 2008 Mar 14;14(10):1539-43. doi: 10.3748/wjg.14.1539.
5
Helicobacter pylori detection and antimicrobial susceptibility testing.幽门螺杆菌检测及抗菌药物敏感性试验。
Clin Microbiol Rev. 2007 Apr;20(2):280-322. doi: 10.1128/CMR.00033-06.
6
Helicobacter pylori DNA in dental plaques, gastroscopy, and dental devices.牙菌斑、胃镜及牙科器械中的幽门螺杆菌DNA
Dig Dis Sci. 2004 Aug;49(7-8):1091-4. doi: 10.1023/b:ddas.0000037793.28069.44.
7
Relationship between gastric disease and deletion of cag pathogenicity island genes of Helicobacter pylori in gastric juice.胃液中幽门螺杆菌cag致病岛基因缺失与胃部疾病的关系。
Dig Dis Sci. 2003 Jan;48(1):47-53. doi: 10.1023/a:1021726213159.
8
Inverse background of Helicobacter pylori antibody and pepsinogen in reflux oesophagitis compared with gastric cancer: analysis of 5732 Japanese subjects.与胃癌相比，反流性食管炎患者幽门螺杆菌抗体和胃蛋白酶原的反向背景：对5732名日本受试者的分析
Gut. 2001 Sep;49(3):335-40. doi: 10.1136/gut.49.3.335.
9
Validation of the string test for the recovery of Helicobacter pylori from gastric secretions and correlation of its results with urea breath test results, serology, and gastric pH levels.用于从胃分泌物中检测幽门螺杆菌的串珠试验的验证及其结果与尿素呼气试验结果、血清学和胃pH值水平的相关性。
J Clin Microbiol. 2001 Apr;39(4):1650-1. doi: 10.1128/JCM.39.4.1650-1651.2001.
10
Culture of Helicobacter pylori from a gastric string may be an alternative to endoscopic biopsy.从胃管中培养幽门螺杆菌可能是内镜活检的一种替代方法。
J Clin Microbiol. 2000 Jun;38(6):2438-9. doi: 10.1128/JCM.38.6.2438-2439.2000.

本文引用的文献

1
Diagnostic tests for Helicobacter pylori: a prospective evaluation of their accuracy, without selecting a single test as the gold standard.幽门螺杆菌的诊断测试：对其准确性的前瞻性评估，未选定单一测试作为金标准。
Am J Gastroenterol. 1996 Oct;91(10):2125-9.
2
Nested-polymerase chain reaction for the detection of Helicobacter pylori infection with novel primers designed by sequence analysis of urease A gene in clinically isolated bacterial strains.利用临床分离菌株脲酶A基因序列分析设计的新型引物，通过巢式聚合酶链反应检测幽门螺杆菌感染。
Biochem Biophys Res Commun. 1996 Feb 6;219(1):266-72. doi: 10.1006/bbrc.1996.0216.
3
Diagnosis of Helicobacter pylori infection by means of a polymerase chain reaction assay for gastric juice aspirates.通过聚合酶链反应检测胃液抽吸物诊断幽门螺杆菌感染
Clin Infect Dis. 1993 Mar;16(3):367-71. doi: 10.1093/clind/16.3.367.
4
Helicobacter pylori infection: independent risk indicator of gastric adenocarcinoma.幽门螺杆菌感染：胃腺癌的独立风险指标。
Gastroenterology. 1993 Oct;105(4):1098-103. doi: 10.1016/0016-5085(93)90954-b.
5
Identification of Helicobacter pylori DNA in the mouths and stomachs of patients with gastritis using PCR.运用聚合酶链反应（PCR）鉴定胃炎患者口腔和胃中的幽门螺杆菌DNA。
J Clin Pathol. 1993 Jun;46(6):540-3. doi: 10.1136/jcp.46.6.540.
6
Effect of age, Helicobacter pylori infection, and gastritis with atrophy on serum gastrin and gastric acid secretion in healthy men.年龄、幽门螺杆菌感染及萎缩性胃炎对健康男性血清胃泌素和胃酸分泌的影响。
Gut. 1993 Aug;34(8):1032-7. doi: 10.1136/gut.34.8.1032.
7
An international association between Helicobacter pylori infection and gastric cancer. The EUROGAST Study Group.幽门螺杆菌感染与胃癌之间的国际关联。欧洲胃癌研究小组。
Lancet. 1993 May 29;341(8857):1359-62.
8
Polymerase chain reaction assay for the detection of Helicobacter pylori in gastric biopsy specimens: comparison with culture, rapid urease test, and histopathological tests.用于检测胃活检标本中幽门螺杆菌的聚合酶链反应分析：与培养、快速尿素酶试验及组织病理学检查的比较
Gut. 1994 Jul;35(7):905-8. doi: 10.1136/gut.35.7.905.
9
NIH Consensus Conference. Helicobacter pylori in peptic ulcer disease. NIH Consensus Development Panel on Helicobacter pylori in Peptic Ulcer Disease.美国国立卫生研究院共识会议。幽门螺杆菌与消化性溃疡病。美国国立卫生研究院消化性溃疡病幽门螺杆菌共识发展小组。
JAMA. 1994 Jul 6;272(1):65-9.
10
Identification of Helicobacter pylori in gastric specimens, gastric juice, saliva, and faeces of Japanese patients.
Lancet. 1994 Jun 25;343(8913):1636-7. doi: 10.1016/s0140-6736(94)93088-0.

使用基于胃液的聚合酶链反应检测培养阴性患者的幽门螺杆菌感染。

Use of a gastric juice-based PCR assay to detect Helicobacter pylori infection in culture-negative patients.

作者信息

Yoshida H, Hirota K, Shiratori Y, Nihei T, Amano S, Yoshida A, Kawamata O, Omata M

机构信息

Second Department of Internal Medicine, University of Tokyo, Japan.

出版信息

J Clin Microbiol. 1998 Jan;36(1):317-20. doi: 10.1128/JCM.36.1.317-320.1998.

DOI:10.1128/JCM.36.1.317-320.1998
PMID:9431979
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC124866/
Abstract

A gastric juice-based PCR assay was compared with culture, microscopy, and a rapid urease test with specimens from 114 subjects. The PCR and conventional tests were positive for 76 and 62% of the subjects, respectively. The prevalence of gastroduodenal disease and seropositivity for anti-Helicobacter pylori immunoglobulin G were similarly high among conventional-test-positive and PCR-only-positive subjects compared to all-negative ones. The PCR assay is recommended to confirm the H. pylori status of culture-negative peptic-ulcer patients.

摘要

将基于胃液的聚合酶链反应（PCR）检测方法与培养法、显微镜检查法以及对114名受试者的标本进行的快速尿素酶试验进行了比较。PCR检测和传统检测的受试者阳性率分别为76%和62%。与所有检测均为阴性的受试者相比，在传统检测阳性和仅PCR检测阳性的受试者中，胃十二指肠疾病的患病率和抗幽门螺杆菌免疫球蛋白G血清阳性率同样较高。建议采用PCR检测来确认培养阴性的消化性溃疡患者的幽门螺杆菌感染状况。