[符拉迪沃斯托克儿童和青少年在针对白喉感染的大规模免疫接种期间对白喉的群体免疫]

[Collective immunity to diphtheria in the children and adolescents of Vladivostok during a mass immunization against this infection].

作者信息

Besednova N N, Kudrina N V, Kuznetsova T A, Zaporozhets T S, Lunika I G, Belogolovkina N A, Ivanova N Iu, Voronok V M

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1997 Sep-Oct(5):82-4.

Abstract

The state of collective immunity to diphtheria in children and adolescents of Vladivostok was studied. Adsorbed DPT vaccine was shown to have higher immunological effectiveness in comparison with adsorbed DT toxoid with reduced antigen content. As revealed in this study, as early as in 2 years a part of the children lost their immunity, irrespective of the preparation used for vaccination, and enlarged the reserve of initially seronegative children and adolescents, capable of maintaining the epidemic process of diphtheria.

摘要

对符拉迪沃斯托克儿童和青少年白喉群体免疫状况进行了研究。结果表明，吸附百白破疫苗相较于抗原含量降低的吸附破伤风类毒素具有更高的免疫效力。本研究显示，早在两年时，部分儿童就丧失了免疫力，无论接种所用制剂如何，且增加了初始血清阴性儿童和青少年的储备量，这些人能够维持白喉的流行过程。