Teresi J A, Holmes D
Columbia University Center for Geriatrics, New York, New York, USA.
Alzheimer Dis Assoc Disord. 1997;11 Suppl 6:146-55.
Assessment of cognitive impairment in chronic care populations is complicated by several factors that may interfere with the assessment process: physical frailty and disability; comorbid conditions such as depression; and decrements in vision, hearing, speech, and general communication. Moreover, cognitive impairment itself affects assessment of outcome domains such as depression, behavior, and function, thus contributing to several sources of measurement bias. Sources of bias are discussed in the context of findings from the literature relating individual and cognitive factors to outcome measurement. Recommendations for further methodological research are provided.
身体虚弱和残疾；诸如抑郁症等合并症；以及视力、听力、言语和一般沟通能力的减退。此外，认知障碍本身会影响对抑郁症、行为和功能等结果领域的评估，从而导致多种测量偏差来源。本文将结合文献中关于个体因素和认知因素与结果测量之间关系的研究结果来讨论偏差来源。并提供了进一步方法学研究的建议。
