MAST CLA过敏系统用于诊断对屋尘螨和猫过敏的评估。

Evaluation of the MAST CLA allergy system for diagnosis of allergies to house dust mites and cats.

作者信息

Ho T M, DeBruynne J, Ahamad M, Darussamin H

机构信息

Institute for Medical Research, Jalan Pahang, Kuala Lumpur, Malaysia.

出版信息

Asian Pac J Allergy Immunol. 1997 Sep;15(3):123-6.

PMID:9438543

Abstract

The MAST CLA system was evaluated against skin prick test (SPT) for diagnosis of allergies to house dust mites (Dermatophagoides pteronyssinus, Dermatophagoides farinae) and cats. Forty three asthmatic children were examined by SPT and MAST CLA. Chi-square analysis indicated significant association between SPT and MAST CLA results for the house dust mites but not for cats. The sensitivities of MAST CLA for house dust mites and cats were 100 and 25% respectively; specificities were all less than 50%. The efficiency of MAST CLA for detection of allergy to the house dust mites was 88% and 44% for cats. A significant linear correlation was found between SPT wheal size and MAST CLA grade for D. farinae but not for D. pteronyssinus and cats. It is concluded that the MAST CLA allergy system can be used to supplement SPT for diagnosis of allergies to house dust mites but not to cats.

摘要

对MAST CLA系统进行了评估，以对照皮肤点刺试验（SPT）诊断对屋尘螨（粉尘螨、户尘螨）和猫的过敏反应。对43名哮喘儿童进行了SPT和MAST CLA检测。卡方分析表明，对于屋尘螨，SPT和MAST CLA结果之间存在显著相关性，但对于猫则不然。MAST CLA对屋尘螨和猫的敏感性分别为100%和25%；特异性均低于50%。MAST CLA检测屋尘螨过敏的效率为88%，检测猫过敏的效率为44%。发现SPT风团大小与粉尘螨的MAST CLA分级之间存在显著线性相关性，但与户尘螨和猫不存在这种相关性。结论是，MAST CLA过敏系统可用于辅助SPT诊断对屋尘螨的过敏反应，但不能辅助诊断对猫的过敏反应。