一名无人类免疫缺陷病毒感染患者的微孢子虫性角膜结膜炎
Microsporidial keratoconjunctivitis in a patient without human immunodeficiency virus infection.
作者信息
Silverstein B E, Cunningham E T, Margolis T P, Cevallos V, Wong I G
机构信息
Francis I. Proctor Foundation, University of California, San Francisco 94122-0944, USA.
出版信息
Am J Ophthalmol. 1997 Sep;124(3):395-6. doi: 10.1016/s0002-9394(14)70833-5.
PURPOSE
To describe a case of microsporidial keratoconjunctivitis in a patient without human immunodeficiency virus (HIV) infection.
METHODS
Case report. An epithelial corneal scraping from a woman with chronic bilateral keratoconjunctivitis was evaluated by Giemsa stain.
RESULTS
Giemsa stain of an epithelial corneal scraping disclosed intracellular and extracellular spores characteristic of microsporidia. An HIV enzyme-linked immunosorbent assay (ELISA) test was negative. The signs and symptoms of the bilateral keratoconjunctivitis resolved after treatment with albendazole.
CONCLUSION
Microsporidia may cause a chronic epithelial keratoconjunctivitis in the absence of HIV infection.
目的
描述一例无人类免疫缺陷病毒（HIV）感染患者的微孢子虫性角膜结膜炎病例。
方法
病例报告。对一名患有慢性双侧角膜结膜炎的女性患者的角膜上皮刮片进行吉姆萨染色评估。
结果
角膜上皮刮片的吉姆萨染色显示出微孢子虫特有的细胞内和细胞外孢子。HIV酶联免疫吸附测定（ELISA）试验为阴性。用阿苯达唑治疗后，双侧角膜结膜炎的体征和症状消失。
结论
在无HIV感染的情况下，微孢子虫可能引起慢性上皮性角膜结膜炎。
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