温泉暴露患者的微孢子菌角膜炎。
Microsporidial keratitis in patients with hot springs exposure.
机构信息
Department of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan.
出版信息
J Clin Microbiol. 2012 Feb;50(2):414-8. doi: 10.1128/JCM.05007-11. Epub 2011 Nov 23.
Abstract
This retrospective study included 10 eyes of 9 patients diagnosed with microsporidial keratitis. All of them were known to contract this disease after taking baths in hot springs. The disease was diagnosed based on detecting microsporidia in corneal scrapings using Gram stain and the modified Kinyoun's acid-fast stain. The specimens from the last six patients were subjected to PCR and then sequencing. All of them revealed that the microorganism identified has a high similarity to Vittaforma corneae. Repeated debridement of the epithelial lesions successfully eradicated the microsporidial infection in all nine patients.
摘要
本回顾性研究纳入了 9 例（10 只眼）患微孢子虫角膜炎的患者。这些患者均已知在温泉洗浴后感染该疾病。通过革兰氏染色和改良金氏酸性染色法在角膜刮片上检测到微孢子虫后确诊该病。对最后 6 例患者的标本进行了 PCR 检测和测序。结果均显示鉴定出的微生物与 Vittaforma corneae 具有高度相似性。对上皮病变进行反复清创，成功根除了 9 例患者的微孢子虫感染。
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