Arikan S, Ergüven S, Günalp A
Hacettepe University, School of Medicine, Department of Clinical Microbiology, Ankara, Turkey.
Zentralbl Bakteriol. 1997 Nov;286(4):487-93. doi: 10.1016/s0934-8840(97)80051-5.
Arcanobacterium haemolyticum (Ah) was isolated from 5 (0.3%) out of 1531 throat cultures of patients with presumed pharyngotonsillitis. The age of the patients who had a positive culture for Ah varied between 6 and 22. The isolation rate of beta-haemolytic streptococci (BHS) was 7.4%, 72.6% of which belonged to Group A, followed by groups G, C and B. None of the throat samples yielded simultaneous growth of Ah and BHS. Antimicrobial susceptibility of Ah isolates to phenoxymethylpenicillin, cephalexin, cefotaxime, vancomycin, erythromycin, azithromycin, doxycycline, ciprofloxacin, and trimethoprim-sulfamethoxazole was tested by the agar dilution method. The isolates were found to be susceptible to all antimicrobials tested except trimethoprim-sulfamethoxazole. Penicillin tolerance could be detected in none of the Ah strains, including the reference strain Ah ATCC 9345. We conclude that Ah should be kept in mind as a potential pathogen causing pharyngitis in adolescents and young adults.
在1531例疑似咽扁桃体炎患者的咽喉培养物中，有5例（0.3%）分离出溶血隐秘杆菌（Ah）。Ah培养阳性患者的年龄在6至22岁之间。β溶血性链球菌（BHS）的分离率为7.4%，其中72.6%属于A组，其次是G、C和B组。咽喉样本中未出现Ah和BHS同时生长的情况。采用琼脂稀释法检测了Ah分离株对苯氧甲基青霉素、头孢氨苄、头孢噻肟、万古霉素、红霉素、阿奇霉素、强力霉素、环丙沙星和甲氧苄啶 - 磺胺甲恶唑的抗菌敏感性。发现分离株对除甲氧苄啶 - 磺胺甲恶唑外的所有测试抗菌药物均敏感。在包括参考菌株Ah ATCC 9345在内的所有Ah菌株中均未检测到青霉素耐受性。我们得出结论，Ah应被视为引起青少年和年轻人咽炎的潜在病原体。
