Gościniak G
Department of Microbiology University of Medicine, Wrocław, Poland.
Zentralbl Bakteriol. 1997 Nov;286(4):494-502. doi: 10.1016/s0934-8840(97)80052-7.
We compared Helicobacter pylori-specific IgG and IgA antibodies in serum, salivary and gastric juice of H. pylori-infected and noninfected patients using the ELISA method. Serum and salivary anti-H. pylori IgG and IgA titres were higher in H. pylori-positive than H. pylori-negative patients. Serum H. pylori IgG titres were higher than those of serum-specific IgA. In contrast, H. pylori IgA titres in saliva samples were higher than those of specific IgG. In all patients, the levels of IgG antibodies were very low in gastric juice. H. pylori-positive patients with increased levels of IgA in sera, also exhibited increased IgA levels in gastric juice. The determination of IgA antibodies in serum and saliva may be used as a test that complements the IgG antibody assay.
我们采用酶联免疫吸附测定（ELISA）法，比较了幽门螺杆菌感染患者和未感染患者血清、唾液及胃液中幽门螺杆菌特异性IgG和IgA抗体。幽门螺杆菌阳性患者血清和唾液中的抗幽门螺杆菌IgG和IgA滴度高于幽门螺杆菌阴性患者。血清幽门螺杆菌IgG滴度高于血清特异性IgA滴度。相比之下，唾液样本中的幽门螺杆菌IgA滴度高于特异性IgG滴度。在所有患者中，胃液中IgG抗体水平非常低。血清中IgA水平升高的幽门螺杆菌阳性患者，其胃液中IgA水平也升高。血清和唾液中IgA抗体的测定可作为一项补充IgG抗体检测的试验。
