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[变应性鼻炎。病理生理学、诊断、鉴别诊断及治疗]

[Allergic rhinitis. Pathophysiology, diagnosis, differential diagnosis and therapy].

作者信息

Bachert C

机构信息

Klinikhoofd, Hals-Nasen-Ohrenklinik der Universität Gent/Belgien.

出版信息

Z Arztl Fortbild Qualitatssich. 1997 Sep;91(6):501-5.

PMID:9441024
Abstract

Allergic diseases caused by inhalant allergens are considered to be a major health problem. Allergic rhinitis, now affecting about 15% of the population, represents an inflammatory reaction, that may lead to asthma and chronic sinusitis as subsequent problems. Diagnosis should be based on a step-by-step concept, that also takes the clinical relevance of sensibilisations and other forms of nasal hyperreactivity into account. The aims of therapy are to limit the inflammatory reaction and to restore patient's quality of life. To achieve this goal, avoidance measures, immunotherapy and antiallergic drugs are currently used. The indication for and the performance of an immunotherapy demands special knowledge, and also the different drug activities and possible side effects should be thoroughly considered.

摘要

吸入性过敏原引起的过敏性疾病被认为是一个主要的健康问题。过敏性鼻炎目前影响着约15%的人口,是一种炎症反应,可能会导致哮喘和慢性鼻窦炎等后续问题。诊断应基于逐步诊断的理念,该理念还应考虑致敏的临床相关性和其他形式的鼻高反应性。治疗的目的是限制炎症反应并恢复患者的生活质量。为实现这一目标,目前采用了避免措施、免疫疗法和抗过敏药物。免疫疗法的适应症和实施需要专业知识,同时还应充分考虑不同药物的活性和可能的副作用。

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