Blanch G, Lavender T, Walkinshaw S, Alfirevic Z
Liverpool Women's Hospital.
Br J Obstet Gynaecol. 1998 Jan;105(1):117-20. doi: 10.1111/j.1471-0528.1998.tb09362.x.
Sixty-one women making slow progress in the active phase of spontaneous labour with intact membranes were randomised to oxytocin and amniotomy, amniotomy only or expectant management. The data show that oxytocin significantly increases the rate of cervical dilatation and shortens prolonged labour, when compared with amniotomy alone and expectant management (P = 0.0144 and 0.0006, respectively). The impact on the operative delivery rate and neonatal outcome is difficult to assess due to the small number of relevant adverse outcomes. Women reported higher satisfaction score in the two groups where intervention followed the diagnosis of dysfunctional labour.
61名在自然分娩活跃期进展缓慢且胎膜完整的女性被随机分为接受催产素和人工破膜组、仅接受人工破膜组或期待治疗组。数据显示，与仅行人工破膜和期待治疗相比，催产素显著提高了宫颈扩张率并缩短了产程延长时间（分别为P = 0.0144和0.0006）。由于相关不良结局数量较少，难以评估其对手术分娩率和新生儿结局的影响。在诊断为产程异常后进行干预的两组中，女性报告的满意度得分更高。
