Barrett-Connor E, Davis C F, Hamburger R N, Kagan I
J Infect Dis. 1976 Apr;133(4):473-7. doi: 10.1093/infdis/133.4.473.
Forty-five percent of young adults who ate roast wild pig at a barbecue in Hawaii experienced an illness compatible with trichinosis. Eosinophilia was present in all of those who were ill and in none who remained well. There were no positive results in skin tests with commercial skin-test antigen. Latex agglutination and counterelectrophoresis were equally good methods for the diagnosis of trichinosis and were more sensitive than the bentonite flocculation test. Levels of IgE in those with illness and eosinophilia were not significantly different from the levels in persons who remained well. It is concluded that skin tests should be abandoned until an improved antigen becomes available, that the relative value of diagnostic serologic methods require continued evaluation, and that levels of IgE may not rise significantly after trichinosis.
在夏威夷一次烧烤活动中食用烤野猪的年轻人中，45%出现了与旋毛虫病相符的病症。所有患病者均出现嗜酸性粒细胞增多，而未患病者均未出现。使用商用皮肤试验抗原来进行皮肤试验，结果均为阴性。乳胶凝集试验和对流免疫电泳是诊断旋毛虫病同样有效的方法，且比膨润土絮凝试验更敏感。患病且嗜酸性粒细胞增多者的IgE水平与未患病者的水平无显著差异。得出的结论是，在有更好的抗原可用之前应放弃皮肤试验，诊断血清学方法的相对价值需要持续评估，旋毛虫病后IgE水平可能不会显著升高。
