Rojo H P, Quiroga E N, Vattuone M A, Sampietro A R
Cátedra de Fitoquímica, Facultad de Bioquímica, Química y Farmacia, Universidad Nacional de Tucuman.
Biochem Mol Biol Int. 1997 Dec;43(6):1331-8. doi: 10.1080/15216549700205151.
The effects of several alkaloids on the invertase activities of Ricinus communis, Solanum tuberosum, Oryza sativa and Carica papaya were studied. The following alkaloids: caffeine, berberine, strychnine, morphine, ethyl-narceine and nornicotine, have different inhibitory effects on invertase activity. Kinetic studies of the alkaloid inhibition revealed that different alkaloids exhibited diverse types of inhibition of invertase. It was found that alkaloids form reversible complexes with invertases. However cocaine and potato glycoalkaloids were activators of some invertase. The sugar moiety of potato glycoalkaloids were also activators. It is concluded that alkaloids may be effectors of higher plant invertase activity.
研究了几种生物碱对蓖麻、马铃薯、水稻和番木瓜转化酶活性的影响。以下生物碱：咖啡因、小檗碱、士的宁、吗啡、乙基那碎因和去甲烟碱，对转化酶活性具有不同的抑制作用。生物碱抑制作用的动力学研究表明，不同生物碱对转化酶表现出不同类型的抑制作用。发现生物碱与转化酶形成可逆复合物。然而，可卡因和马铃薯糖苷生物碱是某些转化酶的激活剂。马铃薯糖苷生物碱的糖部分也是激活剂。得出的结论是，生物碱可能是高等植物转化酶活性的效应物。
