Kaufman D M, Thal L J, Farmer P M
Neurology. 1976 May;26(5):484-8. doi: 10.1212/wnl.26.5.484.
Unusual and unique features were present in the cases of two patients with central nervous system aspergillosis: One had a previously unreported complication of aspergillosis, extracranial internal carotid artery thrombosis documented by angiography, and in the other patient, cerebral granulomas developed from Aspergillus fumigatus in association with intravenous narcotic abuse. The latter etiologic mechanism was suggested once before. Neither of these patients showed other underlying disease. A detailed neuropathologic examination correlated the salient clinical findings with formation of aspergillosis cerebral granulomata, basilar meningitis, and arterial occlusion. Diagnostic and therapeutic methods in this disease are limited.
其中一名患者出现了先前未报告的曲霉菌病并发症，经血管造影证实为颅外颈内动脉血栓形成；另一名患者因静脉注射麻醉品滥用，由烟曲霉菌引发了脑肉芽肿。后一种病因机制曾被提及过一次。这两名患者均未显示出其他潜在疾病。详细的神经病理学检查将显著的临床发现与曲霉菌性脑肉芽肿、基底脑膜炎和动脉闭塞的形成联系起来。该疾病的诊断和治疗方法有限。
